A Toast to Sir Harold Himsworth

Measurement of insulin action: a tribute to Sir Harold Himsworth.

Sir Harold Himsworth was a renowned clinician and researcher. Among his myriad of accomplishments, he was the first to differentiate diabetes mellitus into 'insulin-sensitive' and 'insulin-insensitive' forms. To help distinguish these two types, he developed the first test to measure insulin sensitivity, the insulin-glucose test. This article reviews Himsworth's pioneer methods and subsequent a...

Sir Harold Percival Himsworth, K.C.B. - 19 May 1905--1 November 1993.

Sir Harold Ridley's vision.

This valediction to the late Sir Harold Ridley commemorates the 50th year of his first publication in the St Thomas’s Hospital Report, describing his pioneer undertaking to research, design, and implant an intraocular lens to correct aphakia. Dissatisfied with the poor acuity and loss of binocular single vision following unilateral cataract extraction and the poor outcome, particularly in child...

Why Syndrome X? From Harold Himsworth to the insulin resistance syndrome.

Although the concept of Syndrome X was introduced in the Banting Medal address of 1988 (Reaven, 1988), the notion that led to its genesis had started approximately 50 years earlier. In this short history, an attempt will be made to trace the two paths of scientific discovery that were formally merged in New Orleans in 1988 to form the scientific foundation of Syndrome X. In addition, the develo...

A Toast to Our History

EDITOR'S NOTE: This article is adapted from the address Ms. Kruger delivered as the recipient of the American Diabetes Association's Outstanding Educator in Diabetes Award for 2017. She delivered the address in June 2017 at the Association's 77th Annual Meeting and Scientific Sessions in San Diego, Calif. A webcast of the speech can be viewed on ADA's DiabetesPro website at https://professional...